Apelin-13 Pretreatment Attenuates Age-Associated Renal Fibrotic Remodeling Following I/R Injury
Won-Seok Oh, Sang Gon Lee, Hyun Tae Kim, Ji-Hyun Moon, Ah-La Choi, Seung Yun Han, Do Kyung Kim, Nam Seob Lee, Young Gil Jeong, Geum-Lan Hong · 2026
Read Apelin-13 Pretreatment Attenuates Age-Associated Renal Fibrotic Remodeling Following I/R Injury by Won-Seok Oh, Sang Gon Lee, Hyun Tae Kim, Ji-Hyun Moon, Ah-La Choi, Seung Yun Han, Do Kyung Kim, Nam Seob Lee, Young Gil Jeong, Geum-Lan Hong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13604551.txt.
Description
Won-Seok Oh and a large team test a natural peptide against kidney scarring in old mice. Their study from twenty twenty-six models injury after blocked blood flow. Ageing worsens kidney injury and the fibrosis that follows. The peptide apelin was given before injury as pretreatment.
Young and aged mice had one kidney artery clamped briefly. Aged injured kidneys scarred worse than young ones. Pre-treated aged mice showed less damage and scarring. Kidney function blood tests tracked the protection. Tissue staining and protein blots confirmed the pattern. Why ageing worsens scarring remains partly unexplained. Apelin joins candidate protectors for elderly kidney patients.
Catalog record
| CREATOR | Won-Seok Oh, Sang Gon Lee, Hyun Tae Kim, Ji-Hyun Moon, Ah-La Choi, Seung Yun Han, Do Kyung Kim, Nam Seob Lee, Young Gil Jeong, Geum-Lan Hong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |