Chicken IDO2 and TDO2: Biochemical Characteristics and Regulatory Roles in Avian Tryptophan Metabolism and Inflammatory Response
Wanli Li, Chen Zhang, Pinhui Wu, Kangfei Feng, Guozhi Zhang, Lin Yuan, Wei Jin, Bingxun Wang, Shengli Li, Wei Liu, Wenqing Li · 2026
Read Chicken IDO2 and TDO2: Biochemical Characteristics and Regulatory Roles in Avian Tryptophan Metabolism and Inflammatory Response by Wanli Li, Chen Zhang, Pinhui Wu, Kangfei Feng, Guozhi Zhang, Lin Yuan, Wei Jin, Bingxun Wang, Shengli Li, Wei Liu, Wenqing Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13603309.txt.
Description
Wanli Li and colleagues characterized two chicken enzymes in two thousand twenty-six that control how chickens break down tryptophan, an amino acid tied to immunity. Chickens are unusual: they lack the main enzyme other vertebrates use and rely on these two instead. Diet trials, gene profiling, and lab-made enzymes filled the knowledge gap.
Extra dietary tryptophan kept blood levels steady while switching on liver breakdown pathways and shifting fat and energy balance. Liver enzyme activity rose sharply with little change in gene or protein amounts, pointing to control after production. The enzymes worked best at chicken body conditions. Poultry scientists gain basics for feed design.
Catalog record
| CREATOR | Wanli Li, Chen Zhang, Pinhui Wu, Kangfei Feng, Guozhi Zhang, Lin Yuan, Wei Jin, Bingxun Wang, Shengli Li, Wei Liu, Wenqing Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |