Method for assessing inter-individual variability in the carbohydrate utilization potential of gut microbiota ex vivo
Rachel E Asbury, Taryn A Hoffman, Cathy Chu, Radhakrishnan Mahadevan, Bradley A Saville · 2026
Read Method for assessing inter-individual variability in the carbohydrate utilization potential of gut microbiota ex vivo by Rachel E Asbury, Taryn A Hoffman, Cathy Chu, Radhakrishnan Mahadevan, Bradley A Saville (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13602313.txt.
Description
Rachel Asbury and four co-authors present a lab method to compare how gut microbes from different people use carbohydrates, in a 2026 paper. Microbe use of carbohydrates yields helpful byproducts, such as short fatty acids. Those byproducts are absorbed fast in the body, so they are hard to study there. Growing microbes in culture gives controlled conditions instead.
Their method uses small deep-well plates for batch cultures of stool samples. Steps for collecting, processing, and storing samples are set out in full. Most test carbohydrates were fully or nearly used within a day. Differences between people showed up within twelve hours. Both use speed and byproduct output varied by donor. The authors describe the method as easy and cheap to run. It can screen many donors for gut health research.
Catalog record
| CREATOR | Rachel E Asbury, Taryn A Hoffman, Cathy Chu, Radhakrishnan Mahadevan, Bradley A Saville |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 99 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |