Comparative developmental toxicity and oxidative stress of synthetic and natural yellow food colorants in zebrafish (Danio rerio) embryos

Mahdieh Kiannezhad, Jalal Hassan, Mohammad Kazem Koohi, Amir Moghaddam Jafari · 2026

Read Comparative developmental toxicity and oxidative stress of synthetic and natural yellow food colorants in zebrafish (Danio rerio) embryos by Mahdieh Kiannezhad, Jalal Hassan, Mohammad Kazem Koohi, Amir Moghaddam Jafari (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13602258.txt.

Description

Mahdieh Kiannezhad and co-authors compare harm from one factory made and two plant based yellow food dyes in fish embryos. Their paper from 2026 uses zebrafish, a standard early life test animal. Proof on how such dyes compare in development harm has been thin.

Embryos were dosed from two to ninety six hours after fertilization, across a wide range. Survival, hatching, body faults, lethal and effect doses, and a stress marker were all tracked. Safflower extract proved most toxic overall, with the lowest lethal dose. The factory dye tartrazine caused strong dose tied faults, like heart and yolk swelling and spine bends. Saffron came out mildest, with few faults seen.

Catalog record

CREATORMahdieh Kiannezhad, Jalal Hassan, Mohammad Kazem Koohi, Amir Moghaddam Jafari
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13602258

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