TROP2 expression in gastric and GEJ adenocarcinomas: associations with clinicopathological features, biomarkers, and treatment outcomes
Y Tong, I Nakayama, N Sakamoto, Y Miyashita, Y Shiba, U Hirotaka, Y Sugawara, D Okemoto, K Yamamoto, K Seguchi, T Ogura, Y Matsubara, T Hashimoto, S Mishima, D Kotani, A Kawazoe, Y Kuboki, H Bando, T Kojima, T Yoshino, K Shitara · 2026
Read TROP2 expression in gastric and GEJ adenocarcinomas: associations with clinicopathological features, biomarkers, and treatment outcomes by Y Tong, I Nakayama, N Sakamoto, Y Miyashita, Y Shiba, U Hirotaka, Y Sugawara, D Okemoto, K Yamamoto, K Seguchi, T Ogura, Y Matsubara, T Hashimoto, S Mishima, D Kotani, A Kawazoe, Y Kuboki, H Bando, T Kojima, T Yoshino, K Shitara (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13602217.txt.
Description
Y Tong and a large team mapped a surface protein in two thousand twenty-six across stomach and junction cancers. The protein, TROP2, shows up often in solid tumours and is a drug target, but its spread and meaning in these cancers were unclear. They tested two hundred seventy-two patients with a broad marker panel.
TROP2 appeared in most tumours at each cut-off level they tried. Higher levels paired with more male patients, junction tumours, a certain tissue type, and liver spread. Many TROP2-high patients lacked all four other key markers, which could matter for drug choice. Expression did not link to treatment outcomes in their data.
Catalog record
| CREATOR | Y Tong, I Nakayama, N Sakamoto, Y Miyashita, Y Shiba, U Hirotaka, Y Sugawara, D Okemoto, K Yamamoto, K Seguchi, T Ogura, Y Matsubara, T Hashimoto, S Mishima, D Kotani, A Kawazoe, Y Kuboki, H Bando, T Kojima, T Yoshino, K Shitara |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |