Corticosteroid Tapering After Remission: How Much is Enough?
Sumedh Jayanti, Bhadran Bose · 2026
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Description
Sumedh Jayanti and Bhadran Bose discuss how slowly steroid drugs should be withdrawn after a kidney condition settles, in this 2026 article. The conditions in question are kidney filter diseases that answer to steroids, chiefly minimal change disease and a scarring form called FSGS. Remission is common, but relapse is too: half or more of adults relapse at least once, and some become dependent on the drug.
Guidelines advise long steroid courses for relapsing disease yet say little about the taper, the gradual dose reduction at the end. Tradition stretches tapers over months, from fear that a fast stop invites relapse. The authors review the evidence for shorter tapers and ask how much steroid is enough. The balance is real: longer treatment guards the kidney but adds weight gain, diabetes risk, and bone harm, so the shortest safe taper is worth finding.
Catalog record
| CREATOR | Sumedh Jayanti, Bhadran Bose |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 8 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |