Metagenomic landscape of peripancreatic necrotic pus in acute pancreatitis: pathogen ecology, resistance gene profiles, and disease-associated microbial patterns
Haichao Li, Zhenzhen Shi, Ruoxi Zhang, Jinwei Yao, Jia Li, Dachuan Liu · 2026
Read Metagenomic landscape of peripancreatic necrotic pus in acute pancreatitis: pathogen ecology, resistance gene profiles, and disease-associated microbial patterns by Haichao Li, Zhenzhen Shi, Ruoxi Zhang, Jinwei Yao, Jia Li, Dachuan Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13601262.txt.
Description
Haichao Li and co-authors map the microbes in pus from severe abdominal infections, in a 2026 paper. Gene sequencing can name pathogens and their drug resistance genes at once. The team compared pus from acute pancreatitis cases, with and without lasting organ failure, against other abdominal infections in a surgical intensive care unit.
One hundred fifteen patients gave samples through drainage. Pancreatitis cases shared a profile led by known intensive care pathogens. Resistance genes turned up far more often in pancreatitis samples than in the other group, including genes for the strongest drug class. The study also links microbial traits to lasting organ failure, which may guide drug choice in these hard cases.
Catalog record
| CREATOR | Haichao Li, Zhenzhen Shi, Ruoxi Zhang, Jinwei Yao, Jia Li, Dachuan Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |