Construction and expression of recombinant human elastin with biological activities: effect of wound healing in vitro and in vivo
Xiaona Zhang, Enfang Zhou, Baixin Liao, Yiting Wang, Can Xiong, Mingming Jin, Pei Qin, Sheng Xiong · 2026
Read Construction and expression of recombinant human elastin with biological activities: effect of wound healing in vitro and in vivo by Xiaona Zhang, Enfang Zhou, Baixin Liao, Yiting Wang, Can Xiong, Mingming Jin, Pei Qin, Sheng Xiong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13601249.txt.
Description
Xiaona Zhang and seven co-authors published a study in 2026 on lab-made human elastin for healing skin wounds. Elastin gives tissues their spring, but the natural protein barely dissolves, which limits medical use. Making it in bacteria offers a cheap supply with a controlled recipe, so the team built two versions of the human protein.
Both versions passed purification and showed real activity in cell tests. They nudged skin-related cells to multiply and move, and they carried antioxidant power as well. In mouse skin wounds the proteins sped healing, calming inflammation, laying down collagen, and raising factors that grow new blood vessels. A springy, soluble human protein could become a dressing ingredient for stubborn wounds.
Catalog record
| CREATOR | Xiaona Zhang, Enfang Zhou, Baixin Liao, Yiting Wang, Can Xiong, Mingming Jin, Pei Qin, Sheng Xiong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |