Complete response of extensive cutaneous angiosarcoma of the scalp after PD1 immunotherapy combined with radiotherapy: A report of 2 cases

Anna-Sophia Leven, Christoph Pöttgen, Georg Lodde, Lisa Zimmer, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Selma Ugurel · 2026

Read Complete response of extensive cutaneous angiosarcoma of the scalp after PD1 immunotherapy combined with radiotherapy: A report of 2 cases by Anna-Sophia Leven, Christoph Pöttgen, Georg Lodde, Lisa Zimmer, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Selma Ugurel (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13601040.txt.

Description

Anna-Sophia Leven and co-authors report two cases of a rare skin cancer in a 2026 paper. Cutaneous angiosarcoma grows fast, spreads early, and makes up only a small share of soft tissue cancers. On the head and neck it is hard to treat, and five-year survival is low even with surgery, radiation, and drug treatment together.

Both patients had wide disease on the scalp. They received an immune drug that blocks the PD-1 checkpoint, paired with radiation. In both cases the cancer cleared fully. The authors note why this cancer may respond to immune drugs: it carries many mutations and often shows the very markers those drugs target. The cases suggest a path for patients who cannot have wide surgery.

Catalog record

CREATORAnna-Sophia Leven, Christoph Pöttgen, Georg Lodde, Lisa Zimmer, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Selma Ugurel
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE9 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13601040

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