A Cluster of Influenza A(H3N2) Viruses in 2024 From Tasmania, Australia, With Reduced Susceptibility to Baloxavir
Saira Hussain, Charmaine Chia, Ashwin Muraleetharan, Yi‐Mo Deng, Xiaomin Dong, Presa Chanthalavanh, Emi Takashita, Clyde Dapat, Jessica E Miller, Heidi Peck, Raphael T C Lee, Jan Williamson, Louise Cooley, Sebastian Maurer‐Stroh, Ian G Barr · 2026
Read A Cluster of Influenza A(H3N2) Viruses in 2024 From Tasmania, Australia, With Reduced Susceptibility to Baloxavir by Saira Hussain, Charmaine Chia, Ashwin Muraleetharan, Yi‐Mo Deng, Xiaomin Dong, Presa Chanthalavanh, Emi Takashita, Clyde Dapat, Jessica E Miller, Heidi Peck, Raphael T C Lee, Jan Williamson, Louise Cooley, Sebastian Maurer‐Stroh, Ian G Barr (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13601022.txt.
Description
Saira Hussain and co-authors report a cluster of flu viruses with reduced drug response in a 2026 paper. The viruses, of the A(H3N2) type, turned up in Tasmania, Australia, in 2024. They carried a change in a gene tied to how the antiviral baloxavir works. Such changes matter because they can shrink the drug's power during treatment.
Lab tests showed the change raised the drug amount needed to stop the virus by roughly three to sixteen times over normal strains. When this change was paired with a second known one, the combined virus needed still more drug than the second change alone caused. The authors stress that ongoing watch for reduced drug response stays a core part of flu surveillance, both seasonal and animal-linked.
Catalog record
| CREATOR | Saira Hussain, Charmaine Chia, Ashwin Muraleetharan, Yi‐Mo Deng, Xiaomin Dong, Presa Chanthalavanh, Emi Takashita, Clyde Dapat, Jessica E Miller, Heidi Peck, Raphael T C Lee, Jan Williamson, Louise Cooley, Sebastian Maurer‐Stroh, Ian G Barr |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |