Oral microbiota and serum metabolomics features in newly diagnosed anti-AchR antibody-positive myasthenia gravis patients
Chao Huang, Zhihui Duan, Yan Li, RuiHua Liu, Dandan Shang, Yunting Zhang, Yi Liu, Yuao Wang, Xue Zhao, Yunke Zhang, Feng Gao · 2026
Read Oral microbiota and serum metabolomics features in newly diagnosed anti-AchR antibody-positive myasthenia gravis patients by Chao Huang, Zhihui Duan, Yan Li, RuiHua Liu, Dandan Shang, Yunting Zhang, Yi Liu, Yuao Wang, Xue Zhao, Yunke Zhang, Feng Gao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13600887.txt.
Description
Chao Huang and a large team of co-authors published this 2026 case-control study on the mouth microbes and blood chemistry of people newly diagnosed with myasthenia gravis. The illness is driven by antibodies against the acetylcholine receptor and weakens muscles. Gut germs have drawn much study, but the mix in the mouth had not been looked at. The team recruited 38 untreated patients, half with eye-only disease and half with the generalized form, plus 29 healthy controls.
Saliva went to gene sequencing and blood serum to a broad metabolite scan. Both patient groups showed clear dysbiosis: the Bacillota group of bacteria swelled, while Bacteroidota and Campylobacterota thinned, against the healthy pattern. Links in the data then tied some mouth germs to shifted body chemicals and pathways. The authors frame the mouth as a new window on a body-wide autoimmune illness.
Catalog record
| CREATOR | Chao Huang, Zhihui Duan, Yan Li, RuiHua Liu, Dandan Shang, Yunting Zhang, Yi Liu, Yuao Wang, Xue Zhao, Yunke Zhang, Feng Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |