Organoids Serve as Viable In Vitro Model for Functional Precision Medicine for Mesonephric-Like Adenocarcinoma of the Ovary
David Holthaus, Huy Duc Le, Laura Matzner, Franziska Kellers, Christoph Rogmans, Vincent Winkler, Lorenz Bastian, Stephanie Fliedner, Jörg-Paul Weimer, Hauke Busch, Tim Mandelkow, Björn Konukiewitz, Nicolai Maass, Marion van Mackelenbergh, Ibrahim Alkatout, Dirk O Bauerschlag, Nina Hedemann · 2026
Read Organoids Serve as Viable In Vitro Model for Functional Precision Medicine for Mesonephric-Like Adenocarcinoma of the Ovary by David Holthaus, Huy Duc Le, Laura Matzner, Franziska Kellers, Christoph Rogmans, Vincent Winkler, Lorenz Bastian, Stephanie Fliedner, Jörg-Paul Weimer, Hauke Busch, Tim Mandelkow, Björn Konukiewitz, Nicolai Maass, Marion van Mackelenbergh, Ibrahim Alkatout, Dirk O Bauerschlag, Nina Hedemann (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13600363.txt.
Description
David Holthaus and co-authors published this 2026 study on a rare ovarian cancer and a lab method for testing care. The cancer, called MLA for short, makes up less than 1 percent of ovarian cancers. It was only lately set apart as its own type. The team grew organoids, small lab-grown copies of patient tumors, to see if they can guide treatment choices.
The paper first reviews what is known about this cancer, from its likely cell origins to its signs, such as pelvic pain and bleeding after menopause. Many patients are found only at a late stage. Lab-grown tumor copies let doctors test drugs on a patient's own cancer cells before treating the patient. The work supports that approach for a cancer too rare for large trials.
Catalog record
| CREATOR | David Holthaus, Huy Duc Le, Laura Matzner, Franziska Kellers, Christoph Rogmans, Vincent Winkler, Lorenz Bastian, Stephanie Fliedner, Jörg-Paul Weimer, Hauke Busch, Tim Mandelkow, Björn Konukiewitz, Nicolai Maass, Marion van Mackelenbergh, Ibrahim Alkatout, Dirk O Bauerschlag, Nina Hedemann |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |