Effect of fish oil as an adjunct therapy to metformin on vascular and cardiac health in women with polyendocrine metabolic ovarian syndrome: protocol for a randomised, placebo-controlled clinical trial
Beate Sydora, Mahua Ghosh, Sarah Chambers, Anne Haase, Margie Davenport, Christian Beaulieu, Richard Thompson, Jonathan Windram, Harald Becher, Paolo Raggi, Donna Vine · 2026
Read Effect of fish oil as an adjunct therapy to metformin on vascular and cardiac health in women with polyendocrine metabolic ovarian syndrome: protocol for a randomised, placebo-controlled clinical trial by Beate Sydora, Mahua Ghosh, Sarah Chambers, Anne Haase, Margie Davenport, Christian Beaulieu, Richard Thompson, Jonathan Windram, Harald Becher, Paolo Raggi, Donna Vine (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13599864.txt.
Description
Beate Sydora and co-authors lay out a trial plan on fish oil and heart health in a 2026 paper. The trial serves women with polyendocrine metabolic ovarian syndrome, a hormone and metabolism disorder. It raises heart risk early in life through bad blood fats and insulin problems. The standard drug metformin helps insulin but does little for blood fats. The team will test fish oil as an add-on.
The trial will run at a hospital in Edmonton, Canada, from late 2025 to mid 2028. It will enroll 146 women aged 25 to 45 with high weight and raised blood fats. Half get fish oil with metformin, and half get a dummy pill with metformin, with no one told who gets what. Heart scans and blood tests will track fat levels and early heart change. The plan is a protocol, so results are still to come.
Catalog record
| CREATOR | Beate Sydora, Mahua Ghosh, Sarah Chambers, Anne Haase, Margie Davenport, Christian Beaulieu, Richard Thompson, Jonathan Windram, Harald Becher, Paolo Raggi, Donna Vine |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |