Non‐HLA Antibody‐Associated Hyperacute Allograft Rejection Following Lung Transplantation
Justyna A Karolak, Ernestina Melicoff, Nidhy P Varghese, Przemyslaw Szafranski, Esra Yıldız Bölükbaşı, Erin E McHugh, Sarah Nicholas, Peter Jindra, John Hicks, Eric D Austin, Paweł Stankiewicz, George B Mallory · 2026
Read Non‐HLA Antibody‐Associated Hyperacute Allograft Rejection Following Lung Transplantation by Justyna A Karolak, Ernestina Melicoff, Nidhy P Varghese, Przemyslaw Szafranski, Esra Yıldız Bölükbaşı, Erin E McHugh, Sarah Nicholas, Peter Jindra, John Hicks, Eric D Austin, Paweł Stankiewicz, George B Mallory (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13599712.txt.
Description
Justyna Karolak and co-authors present a case report from two thousand twenty-six on a very fast rejection after lung transplantation in a small child. The boy, aged three, had severe lung vessel disease from a genetic condition and received new lungs without early problems. Hyperacute rejection, where the graft fails almost at once, is extremely rare in lung recipients.
Soon after surgery the graft failed and the team used blood filtering, stronger immune suppression, and a complement-blocking drug. The child died forty-six days after transplant despite that care. A blood sample taken at transplant later tested positive for six antibodies against non-HLA targets, which are not the usual matching antigens. The authors call for more study of such antibodies.
Catalog record
| CREATOR | Justyna A Karolak, Ernestina Melicoff, Nidhy P Varghese, Przemyslaw Szafranski, Esra Yıldız Bölükbaşı, Erin E McHugh, Sarah Nicholas, Peter Jindra, John Hicks, Eric D Austin, Paweł Stankiewicz, George B Mallory |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |