Cerebral autoregulation in the hyperacute phase after experimental subarachnoid haemorrhage using an endovascular perforation model

Michael Veldeman, Erta Beqiri, Marek Czosnyka, Mark Coburn, Anke Höllig, Peter Smielewski · 2026

Read Cerebral autoregulation in the hyperacute phase after experimental subarachnoid haemorrhage using an endovascular perforation model by Michael Veldeman, Erta Beqiri, Marek Czosnyka, Mark Coburn, Anke Höllig, Peter Smielewski (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13599029.txt.

Description

Michael Veldeman and five co-authors study how the brain guards its blood flow in the first hour after a bleed around the brain. In health, the brain holds flow steady as pressure shifts; after such a bleed, that guard may fail. The team re-read data from rats in which a vessel was pierced to mimic the bleed. They tracked blood pressure, skull pressure, and blood flow on both sides of the brain.

On average, the guard held in the first hour. Still, time spent past a danger line rose after the bleed and rose with skull pressure. Two ways of scoring the guard often disagreed. The paper refines how early failure should be judged.

Catalog record

CREATORMichael Veldeman, Erta Beqiri, Marek Czosnyka, Mark Coburn, Anke Höllig, Peter Smielewski
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13599029

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