Feasibility of lattice radiation therapy using a noncoplanar vertex arrangement and dynamic conformal arcs
Haixia Cui, Wei Huang, Xin Yi, Wenli Lu, Qingfeng Jiang · 2026
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Description
Haixia Cui and co-authors propose a simpler way to deliver lattice radiation therapy. The technique peppers a tumor with high-dose spheres. Low-dose valleys separate the spheres. The pattern exploits the contrast between them. Standard planning uses heavy optimization that is slow and can blur the intended peaks and valleys, so the team tested arranging the spheres in a non-flat, three-dimensional pattern with dynamic conformal arcs.
Water phantom experiments compared several sphere geometries, and a one-centimeter sphere spaced four centimeters apart balanced dose contrast against valley sparing best, with all plans keeping complexity low. The same recipe was then applied to two patients with gastrointestinal stromal tumors to check organ sparing and planning time. The authors conclude the geometric approach is feasible and far simpler than inverse optimization, preserving the peak-to-valley structure that makes lattice therapy attractive for bulky tumors.
Catalog record
| CREATOR | Haixia Cui, Wei Huang, Xin Yi, Wenli Lu, Qingfeng Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |