Synergistic association of insomnia and anxiety with cognitive impairment and dementia in older adults
Yan Chen, Qianxi Wang, Ling Li, Shixing Qian, Li Bai, Tih Shih Lee, Shaowei Zhang, Yaping Li, Qianqian Guo, Yang Yang, Feng Yan, Lei Feng, Xia Li · 2026
Read Synergistic association of insomnia and anxiety with cognitive impairment and dementia in older adults by Yan Chen, Qianxi Wang, Ling Li, Shixing Qian, Li Bai, Tih Shih Lee, Shaowei Zhang, Yaping Li, Qianqian Guo, Yang Yang, Feng Yan, Lei Feng, Xia Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13598542.txt.
Description
Yan Chen and co-authors ask whether poor sleep and anxiety together raise the risk of thinking decline in older adults. Their 2026 study uses a Shanghai group of adults aged sixty and over, then checks the pattern in a large British data set. The team tests both conditions alone and paired, and looks at blood markers that might carry part of the link. Paired cases stand out in both data sets.
Having both poor sleep and anxiety is tied to new thinking problems more than either one alone. The British data links the pair to new dementia cases over time as well. Two blood markers carry part of the link, one tied to a harmful brain protein and one to brain support cell stress. The results argue for screening and treating sleep and anxiety as a pair.
Catalog record
| CREATOR | Yan Chen, Qianxi Wang, Ling Li, Shixing Qian, Li Bai, Tih Shih Lee, Shaowei Zhang, Yaping Li, Qianqian Guo, Yang Yang, Feng Yan, Lei Feng, Xia Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |