Unilateral lower limb cellulitis-like edema as an atypical cutaneous manifestation of antisynthetase syndrome: a case report and targeted literature review
Yue Zhang, Jia Su, Ling Zhong, Lan Shang, Huiying Wan · 2026
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Description
Yue Zhang and co-authors present a case report, published in 2026, about a leg swelling that looked like a skin infection but was not. The patient, a woman aged seventy-two, had a week of redness, swelling, and pain in one lower leg. That picture usually means cellulitis, a bacterial skin infection, and fungus found on her foot supported the first guess.
Five days of antibiotics brought no gain, while calf pain, high muscle enzymes, and lung changes appeared. Antibody tests pointed to antisynthetase syndrome, a muscle and lung disease, and a muscle biopsy fit that call. The authors review like cases and warn that one-sided swelling in this syndrome is easily misread as infection. Early antibody testing can save patients from useless antibiotics and delay.
Catalog record
| CREATOR | Yue Zhang, Jia Su, Ling Zhong, Lan Shang, Huiying Wan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |