Refractory Graves’ Disease With Propylthiouracil-Induced Hemophagocytic Lymphohistiocytosis and Multiple Drug Allergies Treated With Total Thyroidectomy: A Case Report
Kenya Kasahara, Hanako Nakajima, Hiroshi Okada, Masahide Hamaguchi, Michiaki Fukui · 2026
Read Refractory Graves’ Disease With Propylthiouracil-Induced Hemophagocytic Lymphohistiocytosis and Multiple Drug Allergies Treated With Total Thyroidectomy: A Case Report by Kenya Kasahara, Hanako Nakajima, Hiroshi Okada, Masahide Hamaguchi, Michiaki Fukui (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13597161.txt.
Description
Kasahara and co-authors present a 2026 case report on Graves' disease that resisted drug treatment. A 43-year-old woman had an overactive thyroid treated with standard antithyroid drugs. A dose rise brought a rash, so doctors switched drugs, and she then developed fever and shock. Tests pointed to a rare immune overreaction triggered by the second drug.
Intensive care, blood cleaning, and immune drugs pulled her through the crisis. Thyroid function worsened again as steroids tapered, and no drug option stayed safe. Sixteen months on, surgery to remove the thyroid settled the disease. The case shows the surgical escape route when drug allergies close every medical door.
Catalog record
| CREATOR | Kenya Kasahara, Hanako Nakajima, Hiroshi Okada, Masahide Hamaguchi, Michiaki Fukui |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |