Dose–response toxicity and locomotor effects of Mucuna pruriens-based phytotherapeutic combinations in pesticide-exposed Drosophila melanogaster
Raphael Mwezi, Maulilio Kipanyula, John – Mary Vianney, Flora Stephano · 2026
Read Dose–response toxicity and locomotor effects of Mucuna pruriens-based phytotherapeutic combinations in pesticide-exposed Drosophila melanogaster by Raphael Mwezi, Maulilio Kipanyula, John – Mary Vianney, Flora Stephano (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13597057.txt.
Description
Raphael Mwezi and three co-authors wrote a 2026 study testing the safety and movement effects of velvet bean remedies in pesticide-exposed fruit flies. Mucuna pruriens seeds contain L-DOPA, the dopamine precursor used against Parkinson's symptoms. Its crude extracts and blends are sold widely, yet their safety is poorly documented.
For toxicity, male flies ate diets with 0.1 to 2.0 percent seed extract for seven days, 180 flies per dose. The team recorded deaths, survival curves, and key thresholds like the median lethal level. Separately, flies were impaired with paraquat or glyphosate, then tested on climbing ability. Blends added pumpkin seed and peanut to the bean. The design checks both harm and benefit across doses. Results inform the safe use of these herbal combinations.
Catalog record
| CREATOR | Raphael Mwezi, Maulilio Kipanyula, John – Mary Vianney, Flora Stephano |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |