Local anesthetic lidocaine decelerates cytoplasmic streaming in Egeria densa via altered actin dynamics and reactive oxygen species generation

Noriyasu Magari, Tomoko Kagenishi, Ken Yokawa · 2026

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Description

Noriyasu Magari, Tomoko Kagenishi, and Ken Yokawa study how a numbing drug slows the flow inside plant cells, in a paper from 2026. The drug is best known for blocking nerve signals in animals, yet it also slows the steady stream that moves parts inside the cells of the pond plant Egeria densa. The team asks what chain of changes links the drug to the slowdown.

Leaf cells slowed in a way that reversed after the drug was washed off. Close views showed the drug broke up the fine actin strands that drive the flow. Tests also found a rise in harsh oxygen based chemicals near the cell wall, tied to calcium entry. When the team added agents that mop up those chemicals, the flow slowed far less.

Catalog record

CREATORNoriyasu Magari, Tomoko Kagenishi, Ken Yokawa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13596920

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