Chitosan activates a sequential Ca 2+ -ROS-NO-jasmonate signaling cascade governing withanolide accumulation in Withania somnifera
Shazia Perveen, Imran Haider, Aqib Mahmood, Sana ur Rehman, Muhammad Yousaf Nadeem, Azatullah Zaheer, Rashed N Herqash, Omar M Noman, Abdullah R Alanzi · 2026
Read Chitosan activates a sequential Ca 2+ -ROS-NO-jasmonate signaling cascade governing withanolide accumulation in Withania somnifera by Shazia Perveen, Imran Haider, Aqib Mahmood, Sana ur Rehman, Muhammad Yousaf Nadeem, Azatullah Zaheer, Rashed N Herqash, Omar M Noman, Abdullah R Alanzi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13596900.txt.
Description
Perveen and co-authors trace the chain of signals by which a shell-derived spray boosts medicine-making in ashwagandha plants. The spray, chitosan, raises output of withanolides, the plant's prized compounds. Working on greenhouse plants, the team blocked one link at a time with targeted drugs and watched what downstream signals died.
A strict order emerged. Calcium surged within minutes, an oxidative burst peaked at three hours, nitric oxide at six, and the hormone jasmonate at twelve. Blocking calcium killed all later steps; blocking each later link spared the earlier ones. By day seven, withanolide output had risen 84 percent, and the early signal sizes predicted the final yield closely.
Catalog record
| CREATOR | Shazia Perveen, Imran Haider, Aqib Mahmood, Sana ur Rehman, Muhammad Yousaf Nadeem, Azatullah Zaheer, Rashed N Herqash, Omar M Noman, Abdullah R Alanzi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 111 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |