Anaerobic bacteria: a neglected reservoir of mobile oxazolidinone resistance genes
Simeng Liu, Shuangyu Xie, Yongshan Song, Ruichao Li, Andrea Brenciani, Stefan Schwarz, Wanjiang Zhang, Yao Zhu · 2026
Read Anaerobic bacteria: a neglected reservoir of mobile oxazolidinone resistance genes by Simeng Liu, Shuangyu Xie, Yongshan Song, Ruichao Li, Andrea Brenciani, Stefan Schwarz, Wanjiang Zhang, Yao Zhu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13596870.txt.
Description
Simeng Liu and co-authors report a 2026 study on hidden drug resistance in gut bacteria. Oxazolidinone drugs are a last resort against hard Gram-positive infections. Genes that defeat them can move between bacteria, and most tracking has focused on germs that live with oxygen.
The team found six gut bacteria that live without oxygen carrying such resistance genes. One gene turned up for the first time in a Gram-negative host, and another in three new host species. Gene maps showed mobile elements that can shuttle the resistance across distant bacterial lines. Other resistance genes sat beside them in the same cells. The authors urge wider tracking of oxygen-free gut bacteria in people and animals.
Catalog record
| CREATOR | Simeng Liu, Shuangyu Xie, Yongshan Song, Ruichao Li, Andrea Brenciani, Stefan Schwarz, Wanjiang Zhang, Yao Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |