Predictors of chronic kidney disease in children who underwent surgical correction of congenital heart disease: a long-term follow-up cohort study
Leonor V. Gotuzzo Mendoza, Antonio Cesar Paulillo de Cillo, Fernando Antonialli, Luciana Bertoldi Nucci, Elisa Teixeira Mendes · 2026
Read Predictors of chronic kidney disease in children who underwent surgical correction of congenital heart disease: a long-term follow-up cohort study by Leonor V. Gotuzzo Mendoza, Antonio Cesar Paulillo de Cillo, Fernando Antonialli, Luciana Bertoldi Nucci, Elisa Teixeira Mendes (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13595991.txt.
Description
Leonor V. Gotuzzo Mendoza and co-authors followed children who had surgery to repair congenital heart defects, asking which of them drift toward chronic kidney disease years later. Their retrospective cohort study measured kidney filtration and protein leakage in the urine during long-term follow-up, hunting for predictors among clinical, surgical, and genetic features.
About one in five patients had developed chronic kidney disease, and protein in the urine, an early injury sign, appeared in about one in six. Carrying a genetic syndrome multiplied the odds of kidney disease roughly fourfold and stood as the sole independent predictor. Operations of lower scored complexity appeared protective by comparison. The authors argue for routine urine screening and lifelong kidney follow-up in this population, with particular vigilance for children whose heart defect comes with a syndrome.
Catalog record
| CREATOR | Leonor V. Gotuzzo Mendoza, Antonio Cesar Paulillo de Cillo, Fernando Antonialli, Luciana Bertoldi Nucci, Elisa Teixeira Mendes |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |