Impact of Reimbursement on the Utilisation of Gene Expression Profiles and Chemotherapy Decision‐Making in Dutch Breast Cancer Patients: A Population‐Based Study

Joyce Meijer, Nienke Hermanns, Rhodé Bijlsma, Hedwig M. Blommestein, Desiree H. J. G. van den Bongard, Thijs van Dalen, Paul J. van Diest, Caroline A. Drukker, Cristina Guerrero Paez, Aafke H. Honkoop, Agnes Jager, Linetta B. Koppert, Sabine C. Linn, Marissa C. van Maaren, Ester J. Siemerink, Laura · 2026

Read Impact of Reimbursement on the Utilisation of Gene Expression Profiles and Chemotherapy Decision‐Making in Dutch Breast Cancer Patients: A Population‐Based Study by Joyce Meijer, Nienke Hermanns, Rhodé Bijlsma, Hedwig M. Blommestein, Desiree H. J. G. van den Bongard, Thijs van Dalen, Paul J. van Diest, Caroline A. Drukker, Cristina Guerrero Paez, Aafke H. Honkoop, Agnes Jager, Linetta B. Koppert, Sabine C. Linn, Marissa C. van Maaren, Ester J. Siemerink, Laura (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13595471.txt.

Description

Joyce Meijer and colleagues examined how reimbursement policy shaped gene-expression testing and chemotherapy decisions in Dutch breast cancer care. From the Netherlands Cancer Registry, 138,765 women aged eighteen to sixty-nine with early-stage cancer diagnosed between 2011 and 2024 were included. Testing rates and chemotherapy use were tracked across reimbursement periods and regions.

Among 17,525 patients with a testing indication, use rose from 9 percent without reimbursement to 25 percent under retrospective reimbursement and 37 percent under publicly known reimbursement. Low-risk test results usually meant no chemotherapy, while high-risk results usually meant chemotherapy. Yet only about a third of eligible patients received a test even when reimbursement was known, a gap the authors flag for follow-up.

Catalog record

CREATORJoyce Meijer, Nienke Hermanns, Rhodé Bijlsma, Hedwig M. Blommestein, Desiree H. J. G. van den Bongard, Thijs van Dalen, Paul J. van Diest, Caroline A. Drukker, Cristina Guerrero Paez, Aafke H. Honkoop, Agnes Jager, Linetta B. Koppert, Sabine C. Linn, Marissa C. van Maaren, Ester J. Siemerink, Laura
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13595471

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