Expression of Concern on ‘ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization’

Julian E Sale, Barry L Stoddard · 2026

Read Expression of Concern on ‘ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization’ by Julian E Sale, Barry L Stoddard (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13594974.txt.

Description

Editors Julian E Sale and Barry L Stoddard issued an expression of concern in 2026 about a 2017 study on the ING1 protein and rRNA levels. The older study, by Rajarajacholan, Thalappilly, and Riabowol, appeared in Nucleic Acids Research. It claimed that ING1 changes the structure of chromatin in the nucleolus and shifts where the mTOR protein sits.

The notice says that in April 2026 the editors learned of possible image problems in four figures, also raised on PubPeer. The worry is that gel and blot bands seem to be copied, both inside the study and from a figure in another journal that showed a different protein. The editors have asked the authors and their institution to look into the matter. Until that review ends, readers are warned to treat the study with extra care.

Catalog record

CREATORJulian E Sale, Barry L Stoddard
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE1 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13594974

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