Lower lipoprotein(a) levels in patients with acute lacunar infarction
Xiangliang Chen, Nihong Chen, Lin Zhu, Qing Huang, Fuping Jiang · 2026
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Description
Xiangliang Chen and co-authors report a surprise link between a blood fat particle and a small-vessel stroke type, in a 2026 study. Lipoprotein(a) is a known risk factor for clogged arteries, yet its tie to lacunar infarction, a stroke from tiny deep brain vessels, was unsettled. The team ran a case-control study in a Chinese population.
They enrolled 989 patients with the stroke type and the same number of matched controls with brain scans. Blood levels of the particle ran lower in the stroke group, not higher. Adjusted models kept the inverse tie, with an odds ratio of 0.76, and it held across age and sex groups. The pattern also showed for strokes in two deep brain zones. The result warns against assuming all artery risks act alike.
Catalog record
| CREATOR | Xiangliang Chen, Nihong Chen, Lin Zhu, Qing Huang, Fuping Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |