Association between serum lipoprotein(a) levels and aortic vulnerable plaques assessed by non-obstructive general angioscopy
Keisuke Kojima, Yudai Tanaka, Katsunori Fukumoto, Yasunari Ebuchi, Tokio Nishiwaki, Naoki Kurito, Satoaki Tomimatsu, Yuta Hotsubo, Tetsuro Nagao, Ran Sumida, Saki Mizobuchi, Shohei Migita, Masatsugu Miyagawa, Koichiro Hori, Yutaka Koyama, Riku Arai, Suguru Migita, Mitsumasa Sudo, Daisuke Fukamachi, · 2026
Read Association between serum lipoprotein(a) levels and aortic vulnerable plaques assessed by non-obstructive general angioscopy by Keisuke Kojima, Yudai Tanaka, Katsunori Fukumoto, Yasunari Ebuchi, Tokio Nishiwaki, Naoki Kurito, Satoaki Tomimatsu, Yuta Hotsubo, Tetsuro Nagao, Ran Sumida, Saki Mizobuchi, Shohei Migita, Masatsugu Miyagawa, Koichiro Hori, Yutaka Koyama, Riku Arai, Suguru Migita, Mitsumasa Sudo, Daisuke Fukamachi, (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13594957.txt.
Description
A fatty particle in the blood called lipoprotein(a) is set largely by genes and raises the risk of cardiovascular disease. Keisuke Kojima and co-authors asked whether high levels also mark fragile plaques in the aorta, the body's main artery. They examined 276 patients with coronary artery disease using a camera technique that views the aorta's inner wall directly, and split the patients by a lipoprotein(a) cutoff of 30 milligrams per deciliter.
About 27 percent had elevated levels. Those patients showed much more plaque rupture, 84 versus 62 percent, plus more clots and fissures, though yellow plaque was equally common. Rupture grew steadily more common across higher lipoprotein(a) bands, and the link survived adjustment for standard risk factors. The authors suggest the particle tracks persistent aortic plaque vulnerability even when cholesterol is well controlled.
Catalog record
| CREATOR | Keisuke Kojima, Yudai Tanaka, Katsunori Fukumoto, Yasunari Ebuchi, Tokio Nishiwaki, Naoki Kurito, Satoaki Tomimatsu, Yuta Hotsubo, Tetsuro Nagao, Ran Sumida, Saki Mizobuchi, Shohei Migita, Masatsugu Miyagawa, Koichiro Hori, Yutaka Koyama, Riku Arai, Suguru Migita, Mitsumasa Sudo, Daisuke Fukamachi, |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |