An immune related cell death index for prognostic stratification and immunotherapy response prediction in oral cancer

Jinglin, Jiao Lu, Guihong Liu, Peijun Qi, Yingying Zong, Hang Yu, Zhaochen Hu, Jing Ding, Zhao Liu, Liangsicheng Tang · 2026

Read An immune related cell death index for prognostic stratification and immunotherapy response prediction in oral cancer by Jinglin, Jiao Lu, Guihong Liu, Peijun Qi, Yingying Zong, Hang Yu, Zhaochen Hu, Jing Ding, Zhao Liu, Liangsicheng Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13594761.txt.

Description

Jinglin and co-authors build a cell death index to sort oral cancer patients by outlook and likely response to immune therapy, in work from twenty twenty-six. Immune linked cell death shapes the tumor's immune neighborhood. No reliable profile of it existed for oral cancer.

Tumors from several data sets first split into hot and cold immune subtypes with clear gaps in immune activity and therapy response. The index, built from death linked genes, then scored each tumor. High scores marked worse outlook and cooler immune activity. Low scores matched stronger immune competence in single cell checks. The index predicted response well in real therapy cohorts and showed drug specific sensitivities.

Catalog record

CREATORJinglin, Jiao Lu, Guihong Liu, Peijun Qi, Yingying Zong, Hang Yu, Zhaochen Hu, Jing Ding, Zhao Liu, Liangsicheng Tang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13594761

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