Effectiveness, safety, and quality of life outcomes of teduglutide treatment in adult patients with short bowel syndrome-associated intestinal failure: A systematic literature review of real-world studies
Shirley C Paski, Anja Becher, Pradeep Nazarey, Kishore Iyer · 2026
Read Effectiveness, safety, and quality of life outcomes of teduglutide treatment in adult patients with short bowel syndrome-associated intestinal failure: A systematic literature review of real-world studies by Shirley C Paski, Anja Becher, Pradeep Nazarey, Kishore Iyer (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13594755.txt.
Description
Shirley Paski and co-authors present a systematic review the catalog lists under 2026. Short bowel syndrome can leave adults unable to absorb enough food, chained to intravenous nutrition. Teduglutide is a drug that helps the remaining gut absorb more, cutting that dependence. Prior reviews only pooled trial-style studies suited to meta-analysis. This review sweeps broader: real-world studies of adults on the drug in ordinary practice. Searches cover two major databases to April 2024 plus key conference proceedings.
Outcomes span effectiveness, safety, and quality of life. Gastroenterologists get the practice-based picture trials cannot give: adherence, long-term tolerance, and life quality outside protocols. Reducing intravenous days is a life-changing endpoint for these patients. Real-world series also catch rare harms that small trials miss. The review sets a baseline for comparing future gut-rehabilitation drugs.
Catalog record
| CREATOR | Shirley C Paski, Anja Becher, Pradeep Nazarey, Kishore Iyer |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |