Dynamic changes in cardiac autonomic function persist in the postacute phase after SARS-CoV-2 infection in a hamster model of COVID-19
Ting Liu, Deepthi Ashok, Andrew Pekosz, Jason Villano, Brian O’Rourke · 2026
Read Dynamic changes in cardiac autonomic function persist in the postacute phase after SARS-CoV-2 infection in a hamster model of COVID-19 by Ting Liu, Deepthi Ashok, Andrew Pekosz, Jason Villano, Brian O’Rourke (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13594463.txt.
Description
Ting Liu and colleagues tracked how COVID-19 reshapes heart nerve control in hamsters over two months. Nerve-control trouble sits at the heart of long COVID, yet how it builds during and after infection is little known. Their 2026 study fitted hamsters with telemetry implants, recorded heart and breathing signals for 56 days after infection, and tested two early treatments.
Nerve control moved in three phases. First came a surge of calming-nerve dominance in days one to four, then a broad slump in days seven to 14, then rising sympathetic and calming inputs from day 28 onward. Early blockade of immune signalling or mitochondrial oxidative stress suppressed the late remodelling. Liu and colleagues frame early immune or stress blockade as a possible route to prevent long-COVID nerve trouble.
Catalog record
| CREATOR | Ting Liu, Deepthi Ashok, Andrew Pekosz, Jason Villano, Brian O’Rourke |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |