Assessing high-throughput surrogate assays for real-world HPV16- and HPV18-specific vaccine immune monitoring: a comparison of PBNA, cCLIA, and IgG

Weiya Mao, Meng Yuan, Zhaoyang Fang, Renyun Zha, Yuxiang Ye, Lin Cai, Linlin Wang, Ruopan Huang, Shuhong Luo, Cheng Guo, Conghui Liao · 2026

Read Assessing high-throughput surrogate assays for real-world HPV16- and HPV18-specific vaccine immune monitoring: a comparison of PBNA, cCLIA, and IgG by Weiya Mao, Meng Yuan, Zhaoyang Fang, Renyun Zha, Yuxiang Ye, Lin Cai, Linlin Wang, Ruopan Huang, Shuhong Luo, Cheng Guo, Conghui Liao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13593855.txt.

Description

Weiya Mao and co-authors compare three blood tests for tracking the immune response to vaccines against the virus that causes cervical cancer. The gold standard test is hard to run at scale, so labs need stand-ins that can handle many samples at speed.

The study drew on people fully vaccinated and on girls given a two dose vaccine over time. All three tests tracked the response to the two virus types in the vaccine. One stand-in held a steadier link to the gold standard than the other, above all over time. Yet both stand-ins gave numbers that could not be swapped one for one with the gold test.

Catalog record

CREATORWeiya Mao, Meng Yuan, Zhaoyang Fang, Renyun Zha, Yuxiang Ye, Lin Cai, Linlin Wang, Ruopan Huang, Shuhong Luo, Cheng Guo, Conghui Liao
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13593855

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