AIComet: a reliable automated scoring program for DNA damage assessment in the comet assay
Adrien Germot, Nicolas Elie, Léonie Ibazizene, Sterenn Guillemot, Poppy Evenden, Peter Møller, Raphaël Delépée, Matthieu Meryet-Figuiere, Pierre Lebailly · 2026
Read AIComet: a reliable automated scoring program for DNA damage assessment in the comet assay by Adrien Germot, Nicolas Elie, Léonie Ibazizene, Sterenn Guillemot, Poppy Evenden, Peter Møller, Raphaël Delépée, Matthieu Meryet-Figuiere, Pierre Lebailly (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13593727.txt.
Description
Adrien Germot and co-authors present AIComet, a 2026 program that scores DNA damage in the comet assay automatically. The assay is a standard test for toxic damage to DNA. Scoring by eye is slow, varies between labs, and misses faint damage. Their model scores images on its own and is open for anyone to use. It was tested against hand scoring in their lab on samples from more than three hundred volunteers. Eleven trained scorers also graded a shared image set for comparison.
More nuclei per sample sharpened the test's sensitivity in their checks. Automation promises the same ruler for every lab. That would cut the wide spread seen between sites today. Biomonitoring studies, which track exposure in workers and the public, stand to gain. The authors report the model's accuracy in detail in the full text. The work is a software validation study.
Catalog record
| CREATOR | Adrien Germot, Nicolas Elie, Léonie Ibazizene, Sterenn Guillemot, Poppy Evenden, Peter Møller, Raphaël Delépée, Matthieu Meryet-Figuiere, Pierre Lebailly |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |