Case Report: Possible spatially-distinct de novo invasive cervical carcinoma in the setting of isolated persistent HPV16 after ALA-PDT-mediated histological clearance of CIN3
Huihui Cai, Yanci Che, Yutong Liu, Jing Wang, Tingting Ma, Rui Yao · 2026
Read Case Report: Possible spatially-distinct de novo invasive cervical carcinoma in the setting of isolated persistent HPV16 after ALA-PDT-mediated histological clearance of CIN3 by Huihui Cai, Yanci Che, Yutong Liu, Jing Wang, Tingting Ma, Rui Yao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13593515.txt.
Description
Huihui Cai and co-authors report a sobering cervical cancer case in a 2026 paper. A thirty-two-year-old woman had severe precancer treated with a light-based therapy that preserves fertility. Tests later showed the lesions gone, yet the cancer-linked virus HPV16 lingered.
Despite repeated reminders, she skipped all check-ups for twenty months. When she returned, doctors found invasive cancer at a different spot on the cervix from the original lesions. The case suggests the persistent virus grew a new cancer on its own, though a hidden second lesion cannot be ruled out without molecular proof. She remained eligible for fertility-sparing surgery. The authors urge risk-based, tighter follow-up for women whose virus persists after treatment.
Catalog record
| CREATOR | Huihui Cai, Yanci Che, Yutong Liu, Jing Wang, Tingting Ma, Rui Yao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |