African swine fever virus remodels cellular host metabolism and promotes lipid droplet formation in macrophages and cell lines
Inmaculada Galindo, Lucía Barrado-Gil, Miguel Ángel Cuesta-Geijo, Stuart D. Armstrong, Isabel García-Dorival, Ana Del Puerto, Jesús Urquiza, Paula Gil-Cortés, Covadonga Alonso · 2026
Read African swine fever virus remodels cellular host metabolism and promotes lipid droplet formation in macrophages and cell lines by Inmaculada Galindo, Lucía Barrado-Gil, Miguel Ángel Cuesta-Geijo, Stuart D. Armstrong, Isabel García-Dorival, Ana Del Puerto, Jesús Urquiza, Paula Gil-Cortés, Covadonga Alonso (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13593491.txt.
Description
Inmaculada Galindo and co-authors wrote a 2026 paper on how African swine fever virus rewires the cells it infects. The virus causes a deadly disease in pigs and threatens pork supplies worldwide. Once inside a cell, it reshapes the cell's activity to favor its own copying. Fat handling is one of the systems it changes.
The team read gene activity in pig lung immune cells at two points after infection. They also ran tests in lab cells, using drugs that block the making of fat droplets. The virus pushed cells to build more of those droplets. Learning which cell systems the virus needs gives scientists targets for drugs or vaccines against a disease that now has few defenses.
Catalog record
| CREATOR | Inmaculada Galindo, Lucía Barrado-Gil, Miguel Ángel Cuesta-Geijo, Stuart D. Armstrong, Isabel García-Dorival, Ana Del Puerto, Jesús Urquiza, Paula Gil-Cortés, Covadonga Alonso |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |