Implementation of a standardized electronic medical record-integrated alternating hyperosmolar therapy protocol in neurocritical care: a single-center retrospective feasibility study

Myriam Semaan, Dania Ghaziri, Wassim Nasreddine, Tarek El Halabi · 2026

Read Implementation of a standardized electronic medical record-integrated alternating hyperosmolar therapy protocol in neurocritical care: a single-center retrospective feasibility study by Myriam Semaan, Dania Ghaziri, Wassim Nasreddine, Tarek El Halabi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13593412.txt.

Description

Four clinicians test a standard protocol for treating brain swelling in a hospital study from 2026. Swelling after brain injury is treated with strong salt or sugar solutions that pull water out. Practice varies widely in dose, timing, and checks. Their unit built a set schedule into the electronic record system, alternating the two fluids every twelve hours over four days.

Seventeen patients were treated under the protocol in two years. Most received at least two days of therapy, and about a third finished all four days. Stops were mostly due to worsening illness or changed care goals, not drug harm. A few patients developed high blood salt levels. The authors call the rollout workable.

Catalog record

CREATORMyriam Semaan, Dania Ghaziri, Wassim Nasreddine, Tarek El Halabi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13593412

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