Dual Antiplatelet Therapy and Very Early Neurological Deterioration after Non-Cardioembolic Stroke According to Stroke Etiology
Rosa Sruthy Pereppadan, Sabrina Schärli, Shania Brülisauer, Francesco Valletta, Dimitrios Vlachos, Thomas R. Schneider, Victoria Hellstern, Gian Marco De Marchis, Tolga D. Dittrich · 2026
Read Dual Antiplatelet Therapy and Very Early Neurological Deterioration after Non-Cardioembolic Stroke According to Stroke Etiology by Rosa Sruthy Pereppadan, Sabrina Schärli, Shania Brülisauer, Francesco Valletta, Dimitrios Vlachos, Thomas R. Schneider, Victoria Hellstern, Gian Marco De Marchis, Tolga D. Dittrich (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13592798.txt.
Description
Rosa Sruthy Pereppadan leads a team asking, in 2026, whether double blood thinner therapy guards against very early decline after certain strokes. Worsening within the first day is common and darkens outlook, yet its ties to drug strategy were murky. Their Swiss center records covered 1,207 adults with strokes not caused by heart clots, admitted between 2014 and 2023. Patients were split by single versus double therapy and by whether artery plaque caused the stroke.
About twenty two percent worsened sharply within a day, more often when plaque was not the cause. After statistical balancing, double therapy pointed toward lower risk in plaque caused strokes but higher risk elsewhere. The second pattern likely reflects sicker patients getting stronger treatment, Pereppadan and the team caution, and they call for prospective trials.
Catalog record
| CREATOR | Rosa Sruthy Pereppadan, Sabrina Schärli, Shania Brülisauer, Francesco Valletta, Dimitrios Vlachos, Thomas R. Schneider, Victoria Hellstern, Gian Marco De Marchis, Tolga D. Dittrich |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |