Exploring sex-specific symptom trajectories in psychosis following metacognitive training (MCT): Evidence from a large-scale retrospective harmonized database
Maria Lamarca, Adrien Goncalves, Steffen Moritz, Łukasz Gawęda, Vanessa Acuña, Caroline König, Fabrice Berna, Susana Ochoa, César González-Blanch · 2026
Read Exploring sex-specific symptom trajectories in psychosis following metacognitive training (MCT): Evidence from a large-scale retrospective harmonized database by Maria Lamarca, Adrien Goncalves, Steffen Moritz, Łukasz Gawęda, Vanessa Acuña, Caroline König, Fabrice Berna, Susana Ochoa, César González-Blanch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13592629.txt.
Description
Maria Lamarca leads a team checking whether sex changes how people with psychosis respond to metacognitive training. The group therapy targets thinking biases behind delusions and related symptoms, and men and women often present differently. Harmonized records from an international consortium covered 573 people with schizophrenia spectrum disorders who took the training in clinics or studies. Symptom scales tracked positive, negative, general, and total scores over time.
Symptoms fell across every domain for the whole group. Yet the pace and size of gains matched between men and women, despite different starting profiles. Sex did not steer the trajectory of change on any scale. Lamarca and the team read the training as broadly usable, while urging finer study of sex linked factors beyond the simple male female split.
Catalog record
| CREATOR | Maria Lamarca, Adrien Goncalves, Steffen Moritz, Łukasz Gawęda, Vanessa Acuña, Caroline König, Fabrice Berna, Susana Ochoa, César González-Blanch |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |