Wearable-Based Assessment for Relapse Prediction Following Repetitive Transcranial Magnetic Stimulation for Depression: Protocol for a Feasibility Study (WARN-D Study)
Clarissa Dine, Zakariya Rekkas, Benicio N Frey, Sridhar Krishnan, Dante Duarte, Fabiano A Gomes, Michael S B Mak, Caroline Wanderley Espinola, Javad Sarvestan · 2026
Read Wearable-Based Assessment for Relapse Prediction Following Repetitive Transcranial Magnetic Stimulation for Depression: Protocol for a Feasibility Study (WARN-D Study) by Clarissa Dine, Zakariya Rekkas, Benicio N Frey, Sridhar Krishnan, Dante Duarte, Fabiano A Gomes, Michael S B Mak, Caroline Wanderley Espinola, Javad Sarvestan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13592458.txt.
Description
Clarissa Dine leads a protocol for a feasibility study on spotting depression relapse early with a smart ring. Magnetic brain stimulation can lift treatment resistant depression, yet many who improve slip back within a year, and no firm warning marker exists. Their pilot will enroll 25 outpatients at two Ontario hospitals. Each will wear an Oura ring through treatment and six months of follow up, with mood, anxiety, sleep, and well being scales taken at set points.
Success will be judged on recruitment, ring adherence, retention, missing data, and ease of use. Exploratory checks will probe whether ring derived signals track treatment response or herald relapse. Dine and the team stress the work is a groundwork step toward larger relapse prevention trials.
Catalog record
| CREATOR | Clarissa Dine, Zakariya Rekkas, Benicio N Frey, Sridhar Krishnan, Dante Duarte, Fabiano A Gomes, Michael S B Mak, Caroline Wanderley Espinola, Javad Sarvestan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |