Synchronous Ovarian and Cervical Malignancies: A Case Report of Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery and Niraparib Maintenance
Xinqi Lv, Lihua Tang, YinPing Ma, Li Zhou · 2026
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Description
Xinqi Lv and co-authors describe one woman carrying three separate gynecological cancers at once. Her left ovary held a carcinosarcoma, her right a high-grade serous carcinoma, and her cervix a squamous cell carcinoma. Such triple primary cancers are exceedingly rare, and no standard playbook covers them. The report walks through her care step by step.
Three rounds of paclitaxel and carboplatin shrank the tumors before interval surgery removed what remained. Five further rounds followed, with bevacizumab in one. Though her tests showed no DNA-repair defect, she then took the maintenance drug niraparib. She stayed free of progression for nearly a year, and lived past three years despite a later ovarian relapse.
Catalog record
| CREATOR | Xinqi Lv, Lihua Tang, YinPing Ma, Li Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |