Non-Linear Association Between Serum Estradiol Decline and Clinical Outcomes in IVF/ICSI Cycles: A Retrospective Cohort Study
Yaying Zhan, Anan Pan, Wei Zhao, Jie Zhang, Muxin Zhai, Haixing Yi, Zhangyun Gong, Hao Wang, Weiqian Zheng, Huanhuan Jiang, Zhimin Lu · 2026
Read Non-Linear Association Between Serum Estradiol Decline and Clinical Outcomes in IVF/ICSI Cycles: A Retrospective Cohort Study by Yaying Zhan, Anan Pan, Wei Zhao, Jie Zhang, Muxin Zhai, Haixing Yi, Zhangyun Gong, Hao Wang, Weiqian Zheng, Huanhuan Jiang, Zhimin Lu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13592331.txt.
Description
Yaying Zhan and ten co-authors study hormone dips during fertility treatment and their link to pregnancy, in a paper published in twenty twenty-six. In IVF cycles, the hormone estradiol is pushed high to grow eggs. A dip before the trigger shot is common, but whether it hurts outcomes was poorly understood.
The team reviewed over eleven hundred patients treated at one center across two years. Hormones were measured at the start and at trigger day, and any dip between checks was scored as a percentage fall. Patients were grouped by whether they conceived and whether they had a live birth. The link between dip size and outcome bent rather than running straight, the title notes. The records give clinics a base for judging when a dip should change plans.
Catalog record
| CREATOR | Yaying Zhan, Anan Pan, Wei Zhao, Jie Zhang, Muxin Zhai, Haixing Yi, Zhangyun Gong, Hao Wang, Weiqian Zheng, Huanhuan Jiang, Zhimin Lu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |