Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition
Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E W Meijer, Rainer Haag · 2026
Read Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition by Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E W Meijer, Rainer Haag (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13592328.txt.
Description
Christian Zoister leads a 2026 team dressing supramolecular fibers with antiviral soap like molecules to block herpes simplex virus. Six new surfactants carry a sulfonate head tuned to grip viral coat proteins. Mixed with water loving fiber forming units, they coat the fibers at low share. Push the share too high and the fibers break into plain micelles, the team found by spectroscopy and microscopy.
Fibrous assemblies stopped the virus at far lower doses than the micellar forms. They also harmed human cells less, likely because the active heads sit locked in the scaffold. Exchange tests showed looser, more dynamic assemblies worked better. Zoister and colleagues present co assembly as a way to aim many weak grips at a virus at once.
Catalog record
| CREATOR | Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E W Meijer, Rainer Haag |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |