Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger · 2026
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Description
Fabienne Weber and four colleagues review, in 2026, how lab made sugars help scholars read and use anti-glycan antibodies. A sugary coat wraps human and microbe cells, and antibodies patrol it for odd patterns that betray germs or cancer. Natural glycans vary wildly, which long blocked clean study. Fresh synthesis routes, including automated assembly lines, now deliver pure, defined structures on demand.
With pure sugars in hand, teams can profile which antibodies a person carries, hunt markers of disease, and raise therapeutic antibodies on purpose. Vaccine design also gains, since exact sugar targets can be built into shots. Weber and the team map these uses and flag the promise for care tailored to each patient's own antibody mix.
Catalog record
| CREATOR | Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 92 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |