Beyond Canonical CO Oxidation: Structural and Evolutionary Insights Into a Non‐Canonical Carbon Monoxide Dehydrogenase
Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land · 2026
Read Beyond Canonical CO Oxidation: Structural and Evolutionary Insights Into a Non‐Canonical Carbon Monoxide Dehydrogenase by Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13592312.txt.
Description
Maximilian Böhm and six colleagues give, in 2026, the first portrait of an enigmatic enzyme family branch that barely burns carbon monoxide. These enzymes normally swap carbon monoxide and carbon dioxide, powering microbe carbon cycles. The branch B version came from a gut bacterium and needed a fully air free imaging workflow the team built for the purpose. Its frozen structure emerged at fine detail.
The portrait shows blocked gas tunnels, a broken proton path, and a warped metal cluster, which explains activity thousands of times below a classic cousin. Family tree checks hint the enzyme instead serves cargo imported by a partner transporter. Böhm and the team read the scaffold as repurposed by evolution for a new, still shadowy job.
Catalog record
| CREATOR | Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40686 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |