The role of exercise in modulating NAD+ metabolic enzymes: mechanisms and health benefits
Anas, Habiba Sundus, Sohrab Ahmed Khan, Syed Suhaib Ahmed, Punitha Muruganantham, Inamul Hasan Madar · 2026
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Description
Anas and five co-authors review how exercise tunes the enzymes that manage NAD+. Their 2026 review centers on a coenzyme vital to cell metabolism. NAD+ feeds enzymes that repair DNA, steer genes, and power mitochondria. Levels fall with age, which may drive many age-linked diseases.
Working out raises the activity of NAD+ makers such as NAMPT. It also boosts sirtuins, enzymes that spend NAD+ on maintenance. Both aerobic and resistance training are covered. The gains improve energy handling and cell balance in studies. The exact pathways from muscle work to enzyme change stay unclear. The review maps what is known and names the open questions.
Catalog record
| CREATOR | Anas, Habiba Sundus, Sohrab Ahmed Khan, Syed Suhaib Ahmed, Punitha Muruganantham, Inamul Hasan Madar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |