Epigallocatechin gallate (EGCG) inhibits African swine fever virus replication by targeting key viral proteins and regulating host lipid metabolism
Xinglin He, Hong Li, Ruiqi Yang, Pengfei Li, Guiqian Wang, Hua Cao, Yumei Sun, Mengjia Zhang, Yongtao Li, Kaizhi Shi, Anan Jongkaewwattana, Shengnan Ruan, Wentao Li · 2026
Read Epigallocatechin gallate (EGCG) inhibits African swine fever virus replication by targeting key viral proteins and regulating host lipid metabolism by Xinglin He, Hong Li, Ruiqi Yang, Pengfei Li, Guiqian Wang, Hua Cao, Yumei Sun, Mengjia Zhang, Yongtao Li, Kaizhi Shi, Anan Jongkaewwattana, Shengnan Ruan, Wentao Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13591956.txt.
Description
Xinglin He and thirteen co-authors test a green tea compound against African swine fever, in this 2026 paper. The virus kills nearly every domestic pig it infects and has battered the world pig industry. Vaccines are approved only in a few places, and no effective drug exists. The compound, EGCG, is the main active catechin in green tea.
In cell tests, EGCG strongly slowed the virus, chiefly at the stages where it enters cells and copies its genome. Binding tests showed it grips two viral proteins the virus cannot do without. It also switched on a host energy sensor, cut fat-making genes, and reversed the fat buildup the virus causes, starving the virus of its needed setting. The authors propose EGCG as a candidate drug with a two-pronged action.
Catalog record
| CREATOR | Xinglin He, Hong Li, Ruiqi Yang, Pengfei Li, Guiqian Wang, Hua Cao, Yumei Sun, Mengjia Zhang, Yongtao Li, Kaizhi Shi, Anan Jongkaewwattana, Shengnan Ruan, Wentao Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |