Reply to the Comment by Finnerup and Gylfadottir Regarding ‘Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain’

Didier Bouhassira, Nadine Attal · 2026

Read Reply to the Comment by Finnerup and Gylfadottir Regarding ‘Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain’ by Didier Bouhassira, Nadine Attal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13591649.txt.

Description

Didier Bouhassira and Nadine Attal answer critics in a 2026 reply letter about their proposed rewrite of how nerve pain is diagnosed. The current grading leans on proving a lesion caused the pain, a link often hard to show. Their convergence model instead weighs several signs together. The critics granted the worry but raised hard cases.

A lesion patient whose pain truly stems from joint wear could pass their test wrongly, the critics note. Classic nerve pains like phantom limb pain might fail it, lacking the usual signs. The authors accept both as limits, arguing rare boundary cases should refine, not sink, the model.

Catalog record

CREATORDidier Bouhassira, Nadine Attal
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE6 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13591649

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