Transforming growth factor-β in kidney disease in dogs and cats: a review of the evidence of its role in renal fibrosis
Rachel E Cianciolo, Jonathan Elliott, Mary B Nabity, Jonathan D Foster, Dylan T Ammons, Katrina Bartas, Tracey Williams, Elizabeth A VanBeelen, Lindsay Weaver · 2026
Read Transforming growth factor-β in kidney disease in dogs and cats: a review of the evidence of its role in renal fibrosis by Rachel E Cianciolo, Jonathan Elliott, Mary B Nabity, Jonathan D Foster, Dylan T Ammons, Katrina Bartas, Tracey Williams, Elizabeth A VanBeelen, Lindsay Weaver (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13591479.txt.
Description
Rachel Cianciolo and co-authors review evidence that a growth factor drives kidney scarring in dogs and cats, in this 2026 paper. The factor is well tied to kidney fibrosis in rodents and humans. Small-animal proof has grown through blood and urine markers, tissue gene reads, and cell culture work.
Strong signs come from natural kidney disease in cats and a genetic model in dogs. Yet lab proof has snags: stains for the active factor in pet tissue are weak and cross-react with its stored form. How the factor wakes scar cells in pets stays open. The authors map agreement and gaps for future work.
Catalog record
| CREATOR | Rachel E Cianciolo, Jonathan Elliott, Mary B Nabity, Jonathan D Foster, Dylan T Ammons, Katrina Bartas, Tracey Williams, Elizabeth A VanBeelen, Lindsay Weaver |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |