Myosteatosis in type 1 diabetes: immunometabolic mechanisms, biomarkers, and therapeutic targets

Fatema Al-Rashed, Halemah AlSaeed, Kevin Patrick Fennelly, Fahd Al Mulla, Rasheed Ahmad · 2026

Read Myosteatosis in type 1 diabetes: immunometabolic mechanisms, biomarkers, and therapeutic targets by Fatema Al-Rashed, Halemah AlSaeed, Kevin Patrick Fennelly, Fahd Al Mulla, Rasheed Ahmad (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13591146.txt.

Description

Fatema Al-Rashed and co-authors review in 2026 fat infiltration of muscle in type 1 diabetes, a problem well known in aging and obesity but barely studied here. Lifelong insulin lack, ongoing autoimmunity, and swinging blood sugar strain muscle energy systems even without obesity. The review pulls together imaging, metabolic, immune, and gene-level evidence into one framework for the condition.

A control axis that normally coordinates fat burning and mitochondrial health gets suppressed by chronic immune activation. Toxic fat byproducts build up, and muscle signaling molecules shift the wrong way. The authors name biomarkers and drug targets that follow from this picture.

Catalog record

CREATORFatema Al-Rashed, Halemah AlSaeed, Kevin Patrick Fennelly, Fahd Al Mulla, Rasheed Ahmad
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13591146

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