A Diagnostic Algorithm Based on Urine Antigen and Blood Polymerase Chain Reaction Testing for Visceral Leishmaniasis in HIV-Coinfected Patients in Northwest Ethiopia
Ermias Diro, Koert Ritmeijer, Saskia van Henten, Aderajew Kibret, Mekibib Kassa, Hailemariam Beyene, Wim Adriaensen, Myrthe Pareyn, Johan van Griensven · 2026
Read A Diagnostic Algorithm Based on Urine Antigen and Blood Polymerase Chain Reaction Testing for Visceral Leishmaniasis in HIV-Coinfected Patients in Northwest Ethiopia by Ermias Diro, Koert Ritmeijer, Saskia van Henten, Aderajew Kibret, Mekibib Kassa, Hailemariam Beyene, Wim Adriaensen, Myrthe Pareyn, Johan van Griensven (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13590951.txt.
Description
Ermias Diro and colleagues tested a safer leishmaniasis diagnosis path in 2026. Visceral leishmaniasis can kill without treatment. HIV co-infection makes diagnosis harder here. Tissue aspiration is risky in these patients. Antibody tests fail this group often.
Urine antigen and blood gene tests were combined. Data came from northwest Ethiopia patients. A step-by-step testing order was assessed. Gene testing followed a positive urine result. Target accuracy goals were mostly met. Specificity fell short of the target though. Fewer invasive procedures would be needed. Scarce resources would stretch further. Noninvasive testing is the core advance.
Catalog record
| CREATOR | Ermias Diro, Koert Ritmeijer, Saskia van Henten, Aderajew Kibret, Mekibib Kassa, Hailemariam Beyene, Wim Adriaensen, Myrthe Pareyn, Johan van Griensven |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |